abstract：:Terfenadine is a safe non-sedative H1-receptor antagonist. This study aimed to quantify the relative reduction in weal and flare area, thickness and erythema at 4, 8, 12 and 24 h following a single but variable oral dose of terfenadine compared with pre-treatment measurements, in order to compare the dose-effect relat...

journal_title：Acta dermato-venereologica

authors： Shall L,Newcombe RG,Lush M,Marks R

更新日期：1991-01-01 00:00:00

abstract：:Thirty lightly pigmented hairless (Hr/Hr) mice were irradiated 5 days per week for 30 weeks to assess the photocarcinogenicity of a new Philips TL 01 narrow-band (311 nm +/- 2) UVB lamp. All mice were found to be tumour-bearing after 16 weeks and histologically, 83% of these had definite squamous cell carcinomas. Comp...

journal_title：Acta dermato-venereologica

authors： Flindt-Hansen H,McFadden N,Eeg-Larsen T,Thune P

更新日期：1991-01-01 00:00:00

abstract：:Previously we observed that systemic CyA induces hair growth in an experimental model of human scalp skin graft transplanted onto nude mice. In the present study we investigated the role of topical CyA in the murine transplantation model, using human split-thickness skin grafts (HSTSG). Ten mice grafted with 1-mm-thic...

journal_title：Acta dermato-venereologica

authors： Gilhar A,Etzioni A,Moscona R

更新日期：1991-01-01 00:00:00

abstract：:We studied by immunohistochemistry the fate of factor XIIIa-positive dermal dendrocytes in Henoch-Schönlein purpura. We have observed apoptosis affecting most of the perivascular dendrocytes. Such an aspect of dendrocytoclasis has never previously been reported in inflammatory disorders in the absence of vasculitis. ...

journal_title：Acta dermato-venereologica

authors： Estrada JA,Goffin F,Cornil F,Pierard-Franchimont C,Pierard GE

更新日期：1991-01-01 00:00:00

abstract：:Inflammatory Linear Verrucous Epidermal Nevus (ILVEN) has been suggested to be a separate disease entity. However, the distinction from linear psoriasis has been discussed in the literature over recent decades. The aim of the present study was to investigate, in addition to the clinical and histological criteria, the ...

journal_title：Acta dermato-venereologica

authors： de Jong E,Rulo HF,van de Kerkhof PC

更新日期：1991-01-01 00:00:00

abstract：:Three different enzyme-linked immunosorbent assays (ELISA) and Western blot were compared in regard to the detection of antibodies to Borrelia burgdorferi in sera from 100 patients with erythema migrans and from 100 controls. For IgG detection, a commercial indirect ELISA kit with flagellum antigen (flagellum ELISA) w...

journal_title：Acta dermato-venereologica

authors： Olsson I,von Stedingk LV,Hanson HS,von Stedingk M,Asbrink E,Hovmark A

更新日期：1991-01-01 00:00:00

abstract：:In order to establish whether or not here is an association between cancer and intense growth of seborrheic keratosis, the so-called Leser-Trelat sign, we conducted a case control study in which the number and features of seborrheic keratosis in 82 patients with recent solid tumours, were compared with 82 age- and sex...

journal_title：Acta dermato-venereologica

authors： Grob JJ,Rava MC,Gouvernet J,Fuentes P,Piana L,Gamerre M,Sarles JC,Bonerandi JJ

更新日期：1991-01-01 00:00:00

abstract：:The regulation of IgE production in B lymphocytes of patients with atopic dermatitis by interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) was studied. IL-4 stimulated IgE production in vitro in B-cells of healthy donors and of children with atopic dermatitis, but had only a marginal effect on the high basal level ...

journal_title：Acta dermato-venereologica

authors： Gruner S,Liebenthal C,Heusser C,Brinkmann V,Zwirner A,Reinicke C,Harnack K,Sönnichsen N,Volk HD

更新日期：1991-01-01 00:00:00

abstract：:To evaluate if whole body UVB irradiation has effects on the neutrophil function, eleven patients with mild to moderate psoriasis and 14 healthy subjects were treated with whole body UVB irradiation 3 times weekly for 4 weeks. Eight healthy untreated subjects served as controls. After 2 weeks of treatment the individu...

journal_title：Acta dermato-venereologica

authors： Lundin A,Michaëlsson G,Venge P,Berne B

更新日期：1990-01-01 00:00:00

abstract：:The effect of UV-light on Pityrosporum yeasts (P.) was studied: P. yeasts cultured from the skin were spread on Dixon plates and irradiated with different UVB-and UVA-light dosages and read after three days, controls were not irradiated. Also P. yeasts, immediately after irradiation, were isolated from the plates and ...

journal_title：Acta dermato-venereologica

authors： Wikler JR,Janssen N,Bruynzeel DP,Nieboer C

更新日期：1990-01-01 00:00:00

abstract：:The ultrastructure of oral lesions in 6 patients with erythema multiforme (EM) and of one apparently clinically healthy oral mucosa in one patient with recurrent EM during remission is described. Alterations were observed in epithelium, basal lamina and lamina propria. Both intercellular and intracellular oedema, intr...

journal_title：Acta dermato-venereologica

authors： Ruokonen H,Hietanen J,Malmström M

更新日期：1990-01-01 00:00:00

abstract：:The possible relationship between skin capacitance and the mechanical properties of the skin was studied using non-invasive techniques. Skin hydration was changed by soaking skin with tap water. Hydration of the skin increased the capacitance significantly (p less than 0.01) and hysteresis (creeping phenomenon) (p les...

journal_title：Acta dermato-venereologica

authors： Jemec GB,Serup J

更新日期：1990-01-01 00:00:00

abstract：:The clinical efficacy and safety of roxithromycin 300 mg once a day was compared with that of erythromycin 500 mg twice a day in 87 men with chlamydia-negative non-gonococcal urethritis. In the roxithromycin group the clinical efficacy rate was 88% on day 8 and between 78% and 84% on day 21. In the erythromycin group ...

journal_title：Acta dermato-venereologica

authors： Worm AM

更新日期：1990-01-01 00:00:00

abstract：:The lysosomal enzyme beta-hexosaminidase and the melanocyte specific enzyme tyrosinase were examined in human melanoma cell cultures. The beta-hexosaminidase activity of the medium was approximately 40% of the total cellular activity after 24 h, while after 48 h the activity in the medium was twice that of the cells. ...

journal_title：Acta dermato-venereologica

authors： Karg E,Hultberg B,Isaksson A,Rosengren E,Rorsman H

更新日期：1990-01-01 00:00:00

abstract：:Horizontal sectioning of scalp biopsies is especially useful in hair diseases characterized by a reduction of follicles in size or number. Horizontal sectioning using standard cryo-microtomes is hampered by the differences in cutting properties between hair follicles and fatty tissue, resulting in loss of topography. ...

journal_title：Acta dermato-venereologica

authors： Van Baar HM,Schalkwijk J,Perret CM

更新日期：1990-01-01 00:00:00

abstract：:The distribution of Fc-receptors for IgG (FcR) on human epidermal cells (EC) was characterized in situ using monoclonal antibodies (MoAbs) by indirect immunofluorescence staining of cryosections. The results showed heterogeneity of FcR expression on Langerhans' cells (LC) and keratinocytes (KC). The MoAb IV.3 against ...

journal_title：Acta dermato-venereologica

authors： Tigalonowa M,Bjerke JR,Livden JK,Matre R

更新日期：1990-01-01 00:00:00

abstract：:Prevalence and severity of seborrhoeic dermatitis were studied in 150 patients with psychiatric disorders, including schizophrenia, mood disorders, anxiety and organic mental illness. As a control group, we examined 150 patients waiting for surgery and regarded as obviously anxious. Thirty-eight psychiatric patients w...

journal_title：Acta dermato-venereologica

authors： Maietta G,Fornaro P,Rongioletti F,Rebora A

更新日期：1990-01-01 00:00:00

abstract：:Retinoid transfer into breast milk was studied in a psoriatric woman receiving oral acitretin at a dosage of 40 mg once daily. Concentrations of the parent compound and its main metabolite, 13-cis acitretin, were measured in serum and mature milk during the initial nine days of therapy, using reverse-phase high perfor...

journal_title：Acta dermato-venereologica

authors： Rollman O,Pihl-Lundin I

更新日期：1990-01-01 00:00:00

abstract：:A man with AIDS is described in whom a profound weight loss was converted into a weight gain by treatment with megoestrol acetate, a synthetic progesterone. His appetite improved and was accompanied by a feeling of improved well-being. Following abrupt discontinuation of the drug, there was a significant but transient...

journal_title：Acta dermato-venereologica

authors： Nathwani D,Green ST,Heslop JM,Goldberg DJ,Kennedy DH

更新日期：1990-01-01 00:00:00

abstract：:The validity of Laser Doppler Flowmetry for measurements of changes in skin blood flow rates during orthostatic manoeuvres was evaluated. Fifteen healthy subjects were investigated. Relative skin blood flow rates on the dorsum of the hand were measured during stepwise raising and lowering of the arm in 10 cm increment...

journal_title：Acta dermato-venereologica

authors： Petersen LJ,Sindrup JH

更新日期：1990-01-01 00:00:00

abstract：:Remission of psoriatic lesions was induced when the lesions were firmly pressed with a plastic cap held in place by an elastic bandage for 24 h or stretched with a negative pressure of 200 mmHg for 2 h. Seven out of 10 patients showed a clinical improvement of the treated psoriatic lesions. These lesions cleared withi...

journal_title：Acta dermato-venereologica

authors： Takematsu H,Tagami H

更新日期：1990-01-01 00:00:00

abstract：:The incidence of malignant melanoma of the skin has increased rapidly among white people during the last decade. Although the pathogenesis of malignant melanoma is not clear, epidemiologic data and experimental work indicates that ultraviolet (UV) radiation plays a critical role in tumorigenesis. Recent data implicate...

journal_title：Acta dermato-venereologica

authors： Reinhold U,Biltz H,Bayer W,Schmidt KH

更新日期：1989-01-01 00:00:00

abstract：:Normal skin and psoriatic lesions from 35 patients were investigated immunohistochemically with regard to the CD1a+ cell population (Langerhans' cells and indeterminate cells) in the epidermis as well as in the dermal infiltrate. In the normal-appearing skin, we found the regularly typical pattern of CD1a+ dendritic c...

journal_title：Acta dermato-venereologica

authors： Bieber T,Braun-Falco O

更新日期：1989-01-01 00:00:00

abstract：:Melanoma tissues produce not only 5-S-cysteinyldopa (5-S-CD), a pheomelanin precursor, but also 5,6-dihydroxyindoles, eumelanin precursors. We compared 5-S-CD and eumelanin-related metabolites regarding the correlation of their production in melanoma and excretion in urine, versus the weight of B16 mouse melanoma. It ...

journal_title：Acta dermato-venereologica

authors： Ito S,Wakamatsu K,Inoue S,Fujita K

更新日期：1989-01-01 00:00:00

abstract：:Biopsies obtained from both the perilesional areas and clinically uninvolved skin of patients with pemphigus vulgaris (PV) were studied for antigen-presenting cell and lymphocyte phenotype and/or activation phenotype using monoclonal antibodies in avidin-biotin-peroxidase complex staining. Perilesional PV skin contain...

journal_title：Acta dermato-venereologica

authors： Mashkilleyson N,Konttinen YT,Visa K

更新日期：1989-01-01 00:00:00

abstract：:A controlled trial of the anti-inflammatory effect of a steroid cream (clobetasol propionate) in 11 patients with moderate acne was assessed over a 3 week period. The placebo cream was the base of the steroid cream. Therapeutic effect was assessed by the number of active and less actively inflamed papules and pustules...

journal_title：Acta dermato-venereologica

authors： Hull SM,Cunliffe WJ

更新日期：1989-01-01 00:00:00

abstract：:The antibody activities and complement fixing ability of the IgG subclass antibodies of herpes gestationis (HG) and bullous pemphigoid (BP) antibodies were investigated. IgG was prepared by DEAE Affi-Gel Blue column. IgG3 and IgG 1.2.4 fractions were isolated through Protein-A Sepharose CL-4B column. In HG, neither Ig...

journal_title：Acta dermato-venereologica

authors： Suzuki M,Watanabe C,Yaoita H

更新日期：1989-01-01 00:00:00

abstract：:In patients with atopic dermatitis, the skin is often 'dry' on non-eczematous areas, and feels rough to the touch. In the scanning electron microscope (SEM) this roughness corresponds to a change in the skin surface, from regular major and minor furrows into a coarse and irregular pattern. In the present study the top...

journal_title：Acta dermato-venereologica

authors： Linde YW,Bengtsson A,Lodén M

更新日期：1989-01-01 00:00:00

abstract：:In a patient affected with acrodermatitis continua Hallopeau, acitretin (Ro 10-1670) monotherapy resulted in a complete clearance of pustulation at a dosage of 45 mg per day. At this dosage the leukotriene B4-induced intraepidermal accumulation of polymorphonuclear leukocytes was markedly inhibited. ...

journal_title：Acta dermato-venereologica

authors： van Dooren-Greebe RJ,van de Kerkhof PC,Chang A,Happle R

更新日期：1989-01-01 00:00:00

abstract：:There are conflicting opinions concerning the epidermal immunofluorescence pattern in primary Sjögren's syndrome. In a prospective study of 12 patients we found a characteristic pattern of epidermal nuclear/cytoplasmic IgG deposits in 8 (67%). This pattern was associated with the presence of antibodies against SSA/Ro ...

journal_title：Acta dermato-venereologica

authors： Velthuis PJ,Nieboer C,Kater L,Hené RJ

更新日期：1989-01-01 00:00:00

abstract：:Blister fluid from tense bullae of 10 patients with bullous pemphigoid was investigated using a radial caseinolysis assay and zymography. Proteolytic activity, varying from 4.7 to 10 micrograms/ml, was found in 3 out of 10 patients, by using the caseinolysis assay. Zymography revealed that a major part of this caseino...

journal_title：Acta dermato-venereologica

authors： Lauharanta J,Salonen EM,Vaheri A

更新日期：1989-01-01 00:00:00

abstract：:The possibility that topically-applied minoxidil might affect the growth cycle of hair follicles was studied in inbred Herston white mice and HRA/Skh1 hairless mice. In the normal follicular cycle, the anagen or growth phase can be followed by autoradiographic demonstration of [3H]thymidine uptake in proliferating mat...

journal_title：Acta dermato-venereologica

authors： Gobé GC,Strutton GM

更新日期：1989-01-01 00:00:00

abstract：:Serum aminoterminal propeptide of type III procollagen (PIIINP) was studied in 73 psoriatics receiving methotrexate and in 11 selected for trial with methotrexate or etretinate. 72 of the patients on methotrexate were also investigated with liver biopsies. The highest PIIINP value was found in a patient with ascites a...

journal_title：Acta dermato-venereologica

authors： Zachariae H,Søgaard H,Heickendorff L

更新日期：1989-01-01 00:00:00

abstract：:Monoamine- and diamine oxidase activities were measured by a sensitive photometric assay in 25 psoriasis vulgaris patients. Results were compared with plasma histamine values determined fluorimetrically. Increased plasma histamine levels were associated with significantly lowered diamine--and type B monoamine oxidase ...

journal_title：Acta dermato-venereologica

authors： Ionescu G,Kiehl R

更新日期：1989-01-01 00:00:00

abstract：:A 10-year follow-up of patients with juvenile plantar dermatosis and gluteo-femoral eczema disclosed a worse prognosis than previously assumed, with a course in some cases protracted into adult age. The presence of atopy was established with a clinical point score system. It was found that 52% of the patients with juv...

journal_title：Acta dermato-venereologica

authors： Svensson A

更新日期：1988-01-01 00:00:00

abstract：:5-S-Cysteinyldopa (5-S-CD), a pheomelanin precursor, has been used as a biochemical marker of melanoma metastasis. Recently, 5-hydroxy-6-methoxyindole-2-carboxylic acid (5H6MI2C), a eumelanin-related metabolite, was shown to reflect well the degree of skin pigmentation. We measured the urinary excretion of 5H6MI2C and...

journal_title：Acta dermato-venereologica

authors： Wakamatsu K,Ito S,Fujita K

更新日期：1988-01-01 00:00:00

abstract：:To elucidate the effect of phototherapy on vitamin D metabolism in psoriatics, the serum concentrations of the major vitamin D metabolites (25-hydroxy-vitamin D (25(OH)D), 1,25-dihydroxy-vitamin D (1,25(OH)2D), and 24,25-dihydroxy-vitamin D (24,25(OH)2D)) were studied in 10 patients with disseminated psoriasis, both b...

journal_title：Acta dermato-venereologica

authors： Staberg B,Oxholm A,Klemp P,Hartwell D

更新日期：1988-01-01 00:00:00

abstract：:Irritant dermatitis after application of experimental irritants was studied by means of contact thermography. Sixteen healthy persons were patch-tested, using the following irritants: Sodium lauryl sulphate, benzalkonium chloride, nonanoic acid, hydrochloric acid, croton oil, sapo kalinus and sodium hydroxide. A main ...

journal_title：Acta dermato-venereologica

authors： Agner T,Serup J

更新日期：1988-01-01 00:00:00

abstract：:1,182 males and 155 females attending an STD clinic from June 1984 to October 1985 were investigated for the presence of antibodies to human immunodeficiency virus (HIV). 348 (29.5%) of the males and 5 (3.2%) of the females were antibody positive (ab+). 237 of the males were initially antibody negative (ab-) and were ...

journal_title：Acta dermato-venereologica

authors： Lindhardt BO,Ulrich K,Sindrup JH,Avnstorp C,Fogh H,Wantzin GL

更新日期：1988-01-01 00:00:00

abstract：:In a prospective study of 63 patients with long-lasting hand eczema, a diagnosis of atopic dermatitis could be established in 49%. Comparison between patients with atopic dermatitis and those without atopic dermatitis showed that the hand eczema pattern differed very little between the groups. Hyperlinearity was signi...

journal_title：Acta dermato-venereologica

authors： Svensson A

更新日期：1988-01-01 00:00:00